Recombinant Human P-selectin Glycoprotein Ligand 1/PSGL-1/CD162 (C-Fc)
Product Sizes
50 µg
£656.00
32-9617-50UG
500 µg
£1534.00
32-9617-500UG
About this Product
- SKU:
- 32-9617
- Additional Names:
- P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162; SELPLG
- Extra Details:
- Source : Human Cells;PSGL-1 (CD162); is a mucintype glycoprotein that plays a key role in leukocyte adhesion. Human PSGL-1 cDNA encodes 412 amino acids (aa). It expressed on neutrophils; monocytes and most lymphocytes. The mature PSGL-1 (aa 42-412) is expressed as a disulfide-linked homodimer that signals intracellularly and promotes integrin activation. PSGL-1 is found on virtually all leukocytes; dendritic cells; platelets; and some endothelial cells. It is primarily responsible for early events in extravasation; especially rolling adhesion of leukocytes to vascular endothelium. Through high affinity; This SLe(x)-type proteoglycanPGSL-1 calcium-dependent interactions with E-; P- and L-selectins; mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
