Recombinant Mouse Pleiotrophin/PTN (C-6His)
Product Sizes
50 µg
£625.00
32-9592-50UG
500 µg
£1515.00
32-9592-500UG
About this Product
- SKU:
- 32-9592
- Additional Names:
- Pleiotrophin; PTN; Heparin-binding brain mitogen; HBBM; Heparin-binding growth factor 8; HBGF-8; Osteoblast-specific factor 1; OSF-1;
- Extra Details:
- Source : Human Cells;Pleiotrophin (PTN) is a secreted; strongly heparinbinding; developmentally regulated cytokine. PTN is a highly conserved protein; Human; mouse; rat; canine; porcine; equine and bovine PTN share 98% aa sequence identity or greater. PTN and midkine share 50% amino acid (aa) sequence identity; share some functions; and constitute a family. During development; PTN is involved in development of brain; bone; and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity; which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated with neuronal development or stresses such as brain ischemia and Parkinson’s disease.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
