Recombinant Mouse Myelin-associated Glycoprotein/Siglec-4a (C-6His)
Product Sizes
50 µg
£614.00
32-9587-50UG
500 µg
£1464.00
32-9587-500UG
About this Product
- SKU:
- 32-9587
- Additional Names:
- Myelin-Associated Glycoprotein; MAG; Siglec-4a
- Extra Details:
- Source : Human Cells;Myelin-Associated Glycoprotein (MAG; Siglec-4a); is a type I transmembrane glycoprotein belonging to the Siglec family. It is composed of an extracellular segment containing five Ig-like domains; a single transmembrane segment; and a cytoplasmic domain. Mouse MAG shares 95% and 99% aa sequence identity with human and rat MAG; respectively. MAG functions as an adhesion molecule during neural development. It preferentially binds to alpha -2;3-linked sialic acid terminal structures found on cell surface molecules. MAG is selectively expressed by myelinating oligodendrocytes and Schwann cells and plays an important role in axon-myelin stability. MAG is also reported to regulate the axon cytoskeleton and support the distribution of axon molecules at the nodes of Ranvier. In addition; it has been identified as a major inhibitor of neurite outgrowth.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
