Recombinant Human T-cell surface glycoprotein CD4/sCD4 (C-Fc)
Product Sizes
50 µg
£656.00
32-9570-50UG
500 µg
£1676.00
32-9570-500UG
About this Product
- SKU:
- 32-9570
- Additional Names:
- T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;CD4;Scd4
- Extra Details:
- Source : Human Cells;CD4 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes. It is a standard phenotype marker for the identification of T cell populations. Mature human CD4 consists of a 371-amino acid extracellular region containing four immunoglobulin-like domains; a 22-aa transmembrane segment; and a 40-aa cytoplasmic domain. CD4 is expressed along with CD8 on double positive T-cells during their development in the thymus. CD4 binds directly to MHC class-II molecules on antigen presenting cells (10). This interaction contributes to the formation of the immunological synapse which is focused around the TCR-MHC class II-antigenic peptide interaction. CD4 also functions as a chemotactic receptor for IL-16 and; in human; as a co-receptor for the gp120 surface glycoprotein of HIV-1.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
