Recombinant Human Complement Component C5a/C5a
Product Sizes
50 µg
£722.00
32-9551-50UG
500 µg
£1959.00
32-9551-500UG
About this Product
- SKU:
- 32-9551
- Additional Names:
- Complement C5; C5a anaphylatoxin; C5a
- Extra Details:
- Source : E. coli;Human Complement 5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. C5a is a 74 amino acid (aa) peptide that is created by the activity of C5a convertase on the C5 -Alpha-chain. Human C5a has four -Alpha-helices plus three intrachain disulfide bonds that create a triple loop structure. Human C5a is 60% and 54% aa identical to mouse and rat C5a; respectively. C5a binds to a signaling G-protein coupled receptor (C5aR/CD88) and a nonsignaling GPCR termed C5L2. Activation of Cd88 results in neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils; and induces release of histamine in basophils and mast cells.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
