Recombinant Human Troponin C/TN-C/TNNC1(N-6His)
Product Sizes
50 µg
£706.00
32-9550-50UG
500 µg
£1726.00
32-9550-500UG
About this Product
- SKU:
- 32-9550
- Additional Names:
- CMH7; TNNC1; TNNI3; Troponin I
- Extra Details:
- Source : E. coli;Troponin I; also known as TNI; is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase; Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins C and T. The expression of cardiac Troponin I (TNNI3) is restricted to cardiac muscle; while TNNI1 and TNNI2 (encoded by distinct genes) are expressed in skeletal muscle. Mutations of cardiac Troponin I are associated with heriditary cardiomyopathy. Human cardiac Troponin I shares 93% amino acid sequence identity with mouse and rat cardiac Troponin I.
- Shipping Conditions:
- Dry Ice
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
