Recombinant Mouse Matrix Metalloproteinase-9/MMP-9
Product Sizes
50 µg
£897.00
32-9393-50UG
500 µg
£2009.00
32-9393-500UG
About this Product
- SKU:
- 32-9393
- Additional Names:
- Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB
- Extra Details:
- Source : Human Cells;Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin; collagen types IV and V; elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by keratinocytes; monocytes; macrophages and PMN leukocytes. MMP-9 is present in most cases of inflammatory responses. Structurally; MMP-9 may be divided into five distinct domains: a prodomain which is cleaved upon activation; a gelatinbinding domain consisting of three contiguous fibronectin type II units; a catalytic domain containing the zinc binding site; a prolinerich linker region; and a carboxyl terminal hemopexinlike domain.
- Shipping Conditions:
- Dry Ice
- Supplier:
- Abeomics
- Type:
- Assay Kits:MMP
- Manufacturer's Data Sheet:download_pdf.php
