Recombinant Mouse CAR/CXADR(C-AVI-6His)
Product Sizes
50 µg
£948.00
32-9363-50UG
500 µg
£2626.00
32-9363-500UG
About this Product
- SKU:
- 32-9363
- Additional Names:
- Coxsackievirus and adenovirus receptor homolog;CAR;Cxadr;CVB3 BP
- Extra Details:
- Source : Human Cells;Coxsackievirus and adenovirus receptor homolog(CAR); also known as CXADR; is a type I transmembrane glycoprotein that belongs to the CTX family of the Ig superfamily. CXADR has monomer subunit that interacts with LNX; BAIAP1; DLG4; PRKCABP; TJP1 and CTNNB1. It also interacts with MPDZ and JAML. CXADR composed of of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. CXADR also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells; a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding; JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
