Recombinant Mouse Mgl2/CD301b(N-6His)
Product Sizes
50 µg
£722.00
32-9360-50UG
500 µg
£1959.00
32-9360-500UG
About this Product
- SKU:
- 32-9360
- Additional Names:
- Mgl2;CD301b;Macrophage galactose N-acetyl-galactosamine-specific lectin 2;Macrophage Galactose-type C-lectin 2
- Extra Details:
- Source : Human Cells;Macrophage galactose N-acetyl-galactosamine-specific lectin 2(Mgl2); also known as CD301b; is a 38 kDa member that belongs to the C-type lectin family. Two MGL proteins are encoded by separate genes in the mouse; but share 91% amino acid (aa) identity in the extracellular domain (ECD). Only one MGL occurs in human and rat and this MGL is structurally more similar to mouse MGL1 than MGL2. However; human MGL and mouse MGL2 both bind specifically to terminal GalNAc residues; in contrast with mouse MGL1 which binds Lewis X. GalNAc recognition is likely to be important in dendritic cell-mediated tolerance to self-gangliosides as well as recognition of tumor antigens and parasite glycoproteins.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
