Recombinant Human Platelet-derived Growth Factor Receptor/PDGF Ralpha (C-6His)
Product Sizes
50 µg
£631.00
32-9299-50UG
500 µg
£1313.00
32-9299-500UG
About this Product
- SKU:
- 32-9299
- Additional Names:
- Platelet-derived growth factor receptor alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor;CD140 antigen-like family member A; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; PDGFR-2; CD140a
- Extra Details:
- Source : Human Cells;Platelet-derived Growth Factor Receptor Alpha (PDGF R-Alpha) is an enzyme that belongs to the class III subfamily of receptor tyrosine kinases.It is a type I transmembrane glycoprotein; and can form homo- or hetero-dimeric receptors when engaged by dimers of the PDGF family of growth factors; PDGF R-Alpha is strongly expressed in oligodendrocyte; lung; skin and intestinal progenitor cells and induced by inflammation or growth in culture; but is lowly expressed in most mesenchymal cells. PDGF R-Alpha autophosphorylates upon dimerization; activating signaling cascades in PI-3kinase Ras-MAP kinase; and PLC-gamma pathways. PDGF R-Alpha has infulence on local gradients of epithelially produced PDGF-AA or PDGF-CC during formation of the cranial ;cardiac neural crest and interstitial kidney mesenchyme.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
