Recombinant Human C-C Motif Chemokine 16/CCL16
Product Sizes
50 µg
£757.00
32-9205-50UG
500 µg
£1959.00
32-9205-500UG
About this Product
- SKU:
- 32-9205
- Additional Names:
- C-C Motif Chemokine 16; Chemokine CC-4; HCC-4; Chemokine LEC; IL-10-Inducible Chemokine; LCC-1; Liver-Expressed Chemokine; Lymphocyte and Monocyte Chemoattractant; LMC; Monotactin-1; MTN-1; NCC-4; Small-Inducible Cytokine A16; CCL16; ILINCK; NCC4; SCYA16
- Extra Details:
- Source : E. coli;CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines; showing less than 30% sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1; CCR2; CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils. CCL16 has potent myelosuppressive activity; suppresses proliferation of myeloid progenitor cells. CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES; suggesting that CCL16 and RANTES share the same receptor in THP1 cells.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
