Recombinant Human Serpin A5 (C-His)
Product Sizes
50 µg
£847.00
32-9194-50UG
500 µg
£1959.00
32-9194-500UG
About this Product
- SKU:
- 32-9194
- Additional Names:
- Plasma Serine Protease Inhibitor; Acrosomal Serine Protease Inhibitor; Plasminogen Activator Inhibitor 3; PAI-3; PAI3; Protein C Inhibitor; PCI; Serpin A5; SERPINA5; PCI; PLANH3; PROCI
- Extra Details:
- Source : Human 293 Cells;Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been found in saliva; cerebral spinal fluid; amniotic fluid; tears and semen. Serpin A5 inhibits various serine protease including thrombin; factor Xa; several kallekreins and acrosin. It also plays an essential role in the processes of blood coagulation and fertilization. Serpin A5 can inhibit urinary plasminogen activator (uPA); a mediator of tumor cell invasion; and regulates tumor growth and metastasis by inhibiting angiogenesis. Furthermore; recent studies have identified PCI as a potent and direct inhibitor of activated HGFA (hepatocyte growth factor activator); indicating a novel function in the regulation of tissue repair and regeneration. Similar to Serpins C1 and D1; the thrombin inhibitory activity of serpinA5 is enhanced by heparin.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
