Recombinant Human Cadherin-11/CDH11 (C-His)
Product Sizes
50 µg
£722.00
32-9180-50UG
500 µg
£1959.00
32-9180-500UG
About this Product
- SKU:
- 32-9180
- Additional Names:
- Cadherin 11 Type 2 OB-cadherin (Osteoblast); Cadherin 11 Type 2 OB-Cadherin (Osteoblast)Isoform CRA_c; CDH11
- Extra Details:
- Source : Human 293 Cells;Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin-11 is expressed in embryonic mesodermal tissues and facilitates the morphogenesis of the nervous and skeletal systems. Cadherins play roles in multiple processes including embryonic development; cell migration; and maintenance of epithelial integrity. Cadherins interact with themselves in a homophilic manner in connecting cells; and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 is up-regulated on breast cancer and prostate cancer cells which preferentially metastasize to bone. It facilitates this metastasis via homophilic adhesion to bone marrow stroma and osteoblast-expressed Cadherin-11. Also; Cadherin-11 is considered a viable molecular target for therapeutic intervention in Glioblastoma multiforme.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
