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Proteins and Peptides

Recombinant Human IL-2RA/CD25 (C-hFc)

Product Sizes
50 µg
£656.00
32-9163-50UG
500 µg
£1464.00
32-9163-500UG
About this Product
SKU:
32-9163
Additional Names:
Interleukin-2 receptor subunit alpha;CD25;p55;TAC antigen;IL2-RA;IL-2R subunit alpha;IL-2-RA;IL-2 receptor subunit alpha;IL-2 R alpha
Extra Details:
Source : Human 293 Cells;Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane glycoprotein; contains 2 Sushi (CCP/SCR) domains. IL2RA is expressed on activated T cells and regulatory T cells; and can bind IL2 with low affinity by itself. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains; together with the common gamma chain (IL2RG); constitute the high-affinity IL2 receptor. While homodimeric alpha chains (IL2RA) result in low-affinity receptor; homodimeric beta (IL2RB) chains produce a medium-affinity receptor. CD25 has been previously regarded as an activation marker on dendritic cells. Although both murine and human dendritic cells can express CD25; they do not express the beta-chain of the IL-2 receptor; which is indispensable for the execution of IL-2 signaling.
Shipping Conditions:
Ambient
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins