Recombinant Human IL-2RA/CD25 (C-Avi&His)
Product Sizes
50 µg
£772.00
32-9152-50UG
500 µg
£2009.00
32-9152-500UG
About this Product
- SKU:
- 32-9152
- Additional Names:
- Interleukin-2 receptor subunit alpha;CD25;p55;TAC antigen;IL2-RA;IL-2R subunit alpha;IL-2-RA;IL2RA;IL-2 receptor subunit alpha
- Extra Details:
- Source : Human 293 Cells;Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane glycoprotein; contains 2 Sushi (CCP/SCR) domains. IL2RA is expressed on activated T cells and regulatory T cells; and can bind IL2 with low affinity by itself. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains; together with the common gamma chain (IL2RG); constitute the high-affinity IL2 receptor. While homodimeric alpha chains (IL2RA) result in low-affinity receptor; homodimeric beta (IL2RB) chains produce a medium-affinity receptor. CD25 has been previously regarded as an activation marker on dendritic cells. Although both murine and human dendritic cells can express CD25; they do not express the beta-chain of the IL-2 receptor; which is indispensable for the execution of IL-2 signaling.
- Shipping Conditions:
- Dry Ice
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
