Biotinylated Recombinant Human Cadherin-1/E-cadherin/CDH1 (C-His)
Product Sizes
25 µg
£722.00
32-9121-25UG
250 µg
£1676.00
32-9121-250UG
About this Product
- SKU:
- 32-9121
- Additional Names:
- Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324
- Extra Details:
- Source : Human 293 Cells;E-Cadherin is a calcium-dependent cell adhesion glycoprotein that belongs to the cadherin family. E-Cadherin is expressed in non-neural epithelial tissues. It tends to interact with each other in a homophilic manner in connecting cells. E-Cadherin clusters are critical components of adherent junctions between epithelial cells and act in the formation and maintenance of the epithelial cell barrier. E-Cadherin is involved in mechanisms regulating cell-cell adhesions; mobility and proliferation of epithelial cells and has a potent invasive suppressor role. E-Cadherin loss contributes to cancer metastasis. The extracellular E-Cadherin N-terminal domain can be cleaved by several proteases and is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
