Recombinant Human Interleukin-7/IL-7 (C-His)
Product Sizes
50 µg
£847.00
32-9107-50UG
500 µg
£2101.00
32-9107-500UG
About this Product
- SKU:
- 32-9107
- Additional Names:
- Interleukin-7; IL-7; IL7
- Extra Details:
- Source : Human 293 Cells;Interleukin 7 (IL-7) is a cytokine that belongs to hemopoietin family. IL-7 is secreted by stromal cells in the red marrow and thymus; and can also be produced by keratinocytes; dendritic cells; hepatocytes; neurons; and epithelial cells; except for lymphocytes. IL-7 stimulates the differentiation of multipotent hematopoietic stem cells into lymphoid progenitor cells. It also induces the proliferation of all cells in the lymphoid lineage (B cells; T cells and NK cells). IL-7 and the hepatocyte growth factor (HGF) together form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT; which regulate lymphocyte survival; glucose uptake; proliferation; and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction. IL-7 has recently been examined in clinical studies as an immunotherapy agent for various malignancies and during HIV infection. Besides; IL-7 could be beneficial in improving immune recovery after allogenic stem cell transplant.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
