Recombinant Mouse Interleukin-11/IL-11 (N-His)
Product Sizes
50 µg
£897.00
32-9082-50UG
500 µg
£2009.00
32-9082-500UG
About this Product
- SKU:
- 32-9082
- Additional Names:
- Interleukin-11; IL-11; Adipogenesis Inhibitory Factor; AGIF; Oprelvekin; IL11
- Extra Details:
- Source : E. coli;Interleukin 11 (IL-11) is a pleiotropic cytokine that belongs to the IL-6 family. As a thrombopoietic growth factor; IL-11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. IL-11 also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2; it activates a signaling cascade that promotes cell proliferation. The signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. IL-11 is found to improve platelet recovery after chemotherapy-induced thrombocytopenia; induce acute-phase proteins; modulate antigen-antibody responses; participate in the regulation of bone cell proliferation and differentiation; and could be used as a therapeutic for osteoporosis.
- Shipping Conditions:
- Dry Ice
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
