Recombinant Human Collagen a-1(VIII) Chain/COL8A1 (C-6His)
Product Sizes
50 µg
£897.00
32-9053-50UG
500 µg
£2009.00
32-9053-500UG
About this Product
- SKU:
- 32-9053
- Additional Names:
- Collagen Alpha-1(VIII) Chain; Endothelial Collagen; Vastatin; COL8A1; C3orf7
- Extra Details:
- Source : Human Cells;Collagen alpha-1(VIII) chain; also known as endothelial collagen; C3orf7 and COL8A1; can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. COL8A1 forms homotrimers or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrahedron stabilized by central interacting C-terminal NC1 trimers. COL8A1 is mainly expressed in the subendothelium of large blood vessels. The expression level can be up-regulated during vascular injury; in atherosclerosis and in diabetes. COL8A1 is necessary for migration and proliferation of vascular smooth muscle cells and thus; has a potential role in the maintenance of vessel wall integrity and structure; in particular in atherogenesis.
- Shipping Conditions:
- Dry Ice
- Supplier:
- Abeomics
- Type:
- Assay Kits:Collagen
- Manufacturer's Data Sheet:download_pdf.php
