Recombinant Mouse B7-1/CD80 (C-His)
Product Sizes
50 µg
£493.00
32-9040-50UG
500 µg
£1009.00
32-9040-500UG
About this Product
- SKU:
- 32-9040
- Additional Names:
- T-lymphocyte activation antigen CD80; Activation B7-1 antigen; B7; CD80
- Extra Details:
- Source : Human 293 Cells;CD80; also known as B7-1; is a member of cell surface immunoglobulin superfamily. CD80 is predominately expressed on the surface of antigen-presenting cells including activated B cells; macrophages and dendritic cells. CD80 and CD86; together with their receptors CD28 and CTLA4; form one of the dominant co-stimulatory pathways that mediate T- and B- cell responses. Although both CD28 and CTLA4 can bind to CD80 and CD86; CTLA-4 has 20-100 fold higher affinity than CD28 plays a role in the down-regulation of the immune response. CD80 is also involved in the induction of innate immune responses by activating NF-kB-signaling pathway in macrophages. Therefore; CD80 has the potential to be promising therapeutic targets for autoimmune diseases and various carcinomas.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
