Recombinant Human Interleukin-10/IL-10 (C-His)
Product Sizes
50 µg
£847.00
32-9036-50UG
500 µg
£2101.00
32-9036-500UG
About this Product
- SKU:
- 32-9036
- Additional Names:
- Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF; IL10; RP11-262N9.1; IL10A;MGC126450; MGC126451; TGIF
- Extra Details:
- Source : Human 293 Cells;Interleukin-10 (IL-10); also known as cytokine synthesis inhibitory factor (CSIF); is a secreted protein that belongs to the IL-10 family. IL-10 is secreted by various mammalian cell types including macrophages; monocytes; T cells; B cells and keratinocytes. As a major immune regulatory cytokine; IL-10 has profound anti-inflammatory functions on many cells of the immune system; limiting excessive tissue disruption caused by inflammation. Studies showed that IL-10 provides a feedback loop to limit the effector functions of macrophages and DCs on T cells. Once expressed; IL-10 signals through the IL-10 receptor (IL-10R) to activate STAT3. In addition to elevated levels in parasitic infection; high expression levels of IL-10 are also found in retroviral infections inducing immunodeficiency. The immunosuppressive properties of IL-10 suggest a possible clinical use of IL-10 in suppressing rejections of grafts after organ transplantations.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
