Recombinant Cynomolgus CD3d / CD3 delta Protein (C-6His)
Product Sizes
10 µg
£508.00
32-8948-10UG
50 µg
£722.00
32-8948-50UG
About this Product
- SKU:
- 32-8948
- Extra Details:
- Source: Human Cells. MW :10.4kD. Recombinant Cynomolgus T-cell Surface Glycoprotein CD3 Delta Chain protein is produced by our Mammalian expression system and the target gene encoding Phe22-Ala105 is expressed with a 6His tag at the C-terminus. T-cell surface glycoprotein CD3 delta chain (CD3D) is a single-pass type I membrane protein. CD3D; together with CD3-gamma; CD3-epsilon and CD3-zeta; and the T-cell receptor alpha/beta and gamma/delta heterodimers; forms the T cell receptor-CD3 complex. CD3 chains are present as CD3gammaepsilon; deltaepsilon; and zetazeta dimers in the receptor complex and play critical roles in the antigen receptor assembly; transport to the cell surface; and the receptor-mediated signal transduction. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. This complex is critical for T-cell development and function; and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs(ITAMs). CD3D contains 1 ITAM domain and has been shown to interact with CD8A.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
