Recombinant Human Fc epsilon RII/CD23 (N-8His)
Product Sizes
10 µg
£499.00
32-8925-10UG
50 µg
£656.00
32-8925-50UG
About this Product
- SKU:
- 32-8925
- Extra Details:
- Source: Human cells. MW :32.1kD. Recombinant Human Low Affinity Fc Epsilon RII is produced by our Mammalian expression system and the target gene encoding Asp48-Ser321 is expressed with a 8His tag at the N-terminus. Low affinity immunoglobulin epsilon Fc receptor(CD23) is a secreted and single-pass type II membrane protein which is also exists as a soluble excreted form. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells; whereas CD23b requires IL-4 to be expressed on T-cells; monocytes; Langerhans cells; eosinophils; and macrophages. Unlike many of the antibody receptors; CD23/FCER2 is a C-type lectin. It is found on mature B cells; activated macrophages; eosinophils; follicular dendritic cells; and platelets. In flow cytometry; CD23/FCER2 is helpful in the differentiation of chronic lymphocytic leukemia (CD23-positive) from mantle cell leukemia (CD23-negative). CD23/FCER2 can also be demonstrated in germinal centre B-cells using immunohistochemistry; but it is not present in the resting cells of the surrounding mantle zone. CD23/FCER2 has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specificantigen).
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
