Recombinant Human Interferon Lambda-2/IL-28A(C-6His)
Product Sizes
10 µg
£508.00
32-8921-10UG
50 µg
£722.00
32-8921-50UG
About this Product
- SKU:
- 32-8921
- Extra Details:
- Source: Human cells. MW :20.6kD. Recombinant Human Interferon Lambda-2 is produced by our Mammalian expression system and the target gene encoding Val26-Val200 is expressed with a 6His tag at the C-terminus. IL-28A (Interferon-lambda2? IFN-lambda2); IL-28B/IFN-lambda3; and IL-29/IFN-lambda1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. Mature human IL-28A is an approximately 22-25 kDa protein that shares 66% amino acid (aa) sequence identity with mouse and rat IL-28A and shows cross-species activity. It shares 96% and 70% aa sequence identity with human IL-28B and IL-29; respectively. IL-28A promotes the Th1 polarization of dendritic cells in the airway and inhibits Th2 and Th17 mediated inflammation. IL-28A additionally exhibits anti-tumor activity; in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast; it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
