Recombinant Rat T-lymphocyte Activation Antigen CD80/B7-1 (C-6His)
Product Sizes
10 µg
£549.00
32-8819-10UG
50 µg
£706.00
32-8819-50UG
About this Product
- SKU:
- 32-8819
- Extra Details:
- Source: Human cells. MW :25.7kD. Recombinant Rat T-lymphocyte Activation Antigen CD81 is produced by our Mammalian expression system and the target gene encoding Vla30-Gln248 is expressed with a 6His tag at the C-terminus. Cluster of Differentiation 80; also called B7-1; is a member of cell surface immunoglobulin superfamily which plays key; yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86; together with their receptors CD28 and CTLA4; constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells; macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands; CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
