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Proteins and Peptides

Recombinant Mouse Thrombopoietin/THPO/TPO (N-6His)

Product Sizes
10 µg
£604.00
32-8803-10UG
50 µg
£897.00
32-8803-50UG
About this Product
SKU:
32-8803
Extra Details:
Source: Human Cells. MW :36.4kD. Recombinant Mouse Thrombopoietin is produced by our expression system and the target gene encoding Ser22­Thr356 is expressed with a 6His tag at the N-terminus. Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets.Mature mouse Tpo shares 71% and 81% aa sequence homology with human and rat Tpo; respectively. It is an 80-85 kDa protein that consists of an N-terminal domain with homology to Erythropoietin (Epo) and a C-terminal domain that contains multiple N-linked and O-linked glycosylation sites. TPO stimulates the production and differentiation of megakaryocytes; the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Shipping Conditions:
Dry Ice
Storage Conditions:
Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins