Recombinant Human Complement Component C3a/C3a
Product Sizes
10 µg
£558.00
32-8785-10UG
50 µg
£772.00
32-8785-50UG
About this Product
- SKU:
- 32-8785
- Extra Details:
- Source: E.coli. MW :9.1kD. Recombinant Human Complement Component C3a is produced by our E.coli expression system and the target gene encoding Ser672-Arg748 is expressed. Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical; alternative and mannose-binding lectin pathways. Complement activation leads to the formation of the C3 convertase; which cleaves C3 into the key effector molecules; C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. By binding to C3a receptor (C3aR); C3a exhibits potent anaphylatoxin activity; including increased vascular permeability; triggering degranulation of mast cells; inflammation; and activating leukocytes.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
