Recombinant Mouse PDGFR a/PDGFRA/CD140a (C-6His)
Product Sizes
10 µg
£549.00
32-8776-10UG
50 µg
£706.00
32-8776-50UG
About this Product
- SKU:
- 32-8776
- Extra Details:
- Source: Human Cells. MW :56.9kD. Recombinant Mouse PDGF receptor alpha is produced by our Mammalian expression system and the target gene encoding Leu25-Glu524 is expressed with a 6His tag at the C-terminus. Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A; -B; -C and -D; which form either homo- or heterodimers (PDGF-AA; -AB; -BB; -CC; -DD). The four PDGFs are inactive in their monomeric forms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-a and - beta. These two receptor isoforms dimerize upon binding the PDGF dimer; leading to three possible receptor combinations; namely -aa; - beta beta and -a beta. PDGFRa and PDGFR beta are members of the class III RTK family. Inappropriate PDGFRa and PDGFR beta signaling has been linked to a number of proliferative disorders.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
