Recombinant Mouse B7-H3/CD276(C-6His)
Product Sizes
10 µg
£528.00
32-8749-10UG
50 µg
£634.00
32-8749-50UG
About this Product
- SKU:
- 32-8749
- Extra Details:
- Source: Human Cells. MW :24.3kD. Recombinant Mouse B7 Homolog 3 is produced by our Mammalian expression system and the target gene encoding Val29-Phe244 is expressed with a 6His tag at the C-terminus. CD276; also known as B7-H3; is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20–27% amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes; and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions; providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells; natural killer cells; and antigen presenting cells; as well as some non-immune cells; such as osteoblasts; fibroblasts; fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature also correlates with poor survival in patients; suggesting that it may play a role in tumor cell migration.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
