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Proteins and Peptides

Recombinant Klebsiella pneumoniae Kanamycin kinase type II/NEO

Product Sizes
10 µg
£558.00
32-8733-10UG
50 µg
£772.00
32-8733-50UG
About this Product
SKU:
32-8733
Extra Details:
Source: E.coli. MW :29kD. Recombinant Klebsiella pneumoniae Aminoglycoside 3'-phosphotransferase is produced by our E.coli expression system and the target gene encoding Met1-Phe264 is expressed. Aminoglycoside 3'-phosphotransferase (APH(3')); also known as aminoglycoside kinase; is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins; neomycins; paromomycins; neamine; ribostamycin; geneticin; and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins