Recombinant E. coli RNA Pyrophosphohydrolase/rppH
Product Sizes
10 µg
£558.00
32-8693-10UG
50 µg
£772.00
32-8693-50UG
About this Product
- SKU:
- 32-8693
- Extra Details:
- Source: E.coli. MW :20.8kD. Recombinant E.coli RNA pyrophosphohydrolase is produced by our E.coli expression system and the target gene encoding Met1-Gly176 is expressed. Messenger RNA (mRNA) degradation plays a key role in the control of gene expression in all organisms by limiting the number of times that each mRNA molecule can be used as a template for protein synthesis. RNA pyrophosphohydrolase; also called RppH; is a master regulator of 5'-dependent mRNA decay. It accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA; leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage. RppH preferentially hydrolyzes diadenosine penta-phosphate with ATP as one of the reaction products; and can be able to hydrolyze diadenosine hexa- and tetra-phosphate. However; this protein has no activity on diadenosine tri-phosphate; ADP-ribose; NADH and UDP-glucose. In the meningitis causing strain E.coli K1; it has been shown to play a role in HBMEC (human brain microvascular endothelial cells) invasion in vitro.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
