Recombinant Human PRL
Product Sizes
10 µg
£493.00
32-8677-10UG
50 µg
£656.00
32-8677-50UG
About this Product
- SKU:
- 32-8677
- Extra Details:
- Source: Human Cells. MW :23.9kD. Recombinant Human Prolactin is produced by our Mammalian expression system and the target gene encoding Leu29-Cys227 is expressed with a 6His tag at the C-terminus. Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation; but has pleiotropic effects in both males and females. Non-glycosylated prolactin is produced by the pituitary and packaged in storage granules before secretion; while glycosylated prolactin is reported to be constitutively secreted; have lower biological potency; and be removed from the circulation more quickly. Prolactin is synthesized mainly by the anterior pituitary in all mammals; where secretion is under tonic inhibition by hypothalamic dopamine. In humans; prolactin is also produced peripherally. Prolactin expression is low during early human pregnancy; but increases in late pregnancy. The prolactin receptor (PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. prolactin molecule is thought to bind two receptor molecules. In addition to its lactogenic activity; peripherally produced prolactin plays roles in breast and prostate cancer development; regulation of reproductive function; and immunoregulation.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
