Recombinant Mouse Kallikrein 7/KLK7 (C-6His)
Product Sizes
10 µg
£554.00
32-8654-10UG
50 µg
£847.00
32-8654-50UG
About this Product
- SKU:
- 32-8654
- Extra Details:
- Source: Human Cells. MW :26.1kD. Recombinant Mouse Kallikrein 7 is produced by our Mammalian expression system and the target gene encoding Gln22-Arg249 is expressed with a 6His tag at the C-terminus. Kallikrein7; also named as stratum corneum chymotryptic enzyme (SCCE); is a secreted protein of the Kallikrein-related peptidase (KLK) family. This family contains fifteen homologous secreted serine endopeptidases and plays a significant role in various physiological processes; including skin desquamation; semen liquefaction; neural plasticity; and body fluid homeostasis. In skin KLK5; KLK 7 and KLK14 are able to degrade corneodesmosomes; which leads to desquamation of skin surface cells. KLK activation is believed to be mediated through highly organized proteolytic cascades; regulated through a series of feedback loops; inhibitors; auto-degradation and internal cleavages. Studies have shown that one potential physiological activator for KLK7 is KLK5. Along with KLK14; these three kallikreins form a proteolytic cascade in the stratum corneum. KLK7 is primarily expressed in the skin but is also detected at relatively high levels in esophagus; heart; liver; central nervous system; kidney; pancreas; mammary and salivary glands.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
