Recombinant Mouse Interleukin-4/IL-4
Product Sizes
10 µg
£499.00
32-8585-10UG
50 µg
£691.00
32-8585-50UG
About this Product
- SKU:
- 32-8585
- Extra Details:
- Source: E.coli. MW :13.4kD. Recombinant Mouse Interleukin-4 is produced by our E.coli expression system and the target gene encoding His23-Ser140 is expressed. Mouse Interleukin-4(IL-4) is a monomeric; Th2 cytokine that shows pleiotropic effects during immune responses. It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four ahelix structure. IL4 exerts its effects through two receptor complexes; Participates in at least several B-cell activation processes as well as of other cell types. IL4 is primarily expressed by Th2biased CD4+T cells; mast cells; basophils; and eosinophils. It promotes cell proliferation; survival; and immunoglobulin class switch to IgG1 and IgE in mouse B cells; acquisition of the Th2 phenotype by naïve CD4+T cells; priming and chemotaxis of mast cells; eosinophils; and basophils; and the proliferation and activation of epithelial cells. IL4 plays a dominant role in the development of allergic inflammation and asthma. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
