Recombinant Human Protein N-terminal Glutamine Amidohydrolase/NTAQ1
Product Sizes
10 µg
£558.00
32-8579-10UG
50 µg
£772.00
32-8579-50UG
About this Product
- SKU:
- 32-8579
- Extra Details:
- Source: E.coli. MW :49.8kD. Recombinant Human NTAQ1 is produced by our E.coli expression system and the target gene encoding Met1-Cys205 is expressed with a GST tag at the N-terminus. Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene; belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate; which is an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation; polyubiquitination and degradation as specified by the N-end rule. However;it does not act on substrates with internal or C-terminal glutamine andnon-glutamine residues in any position. With the exception of proline; all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast; a proline at position 2; virtually abolishes deamidation of N-terminal glutamine.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
