Recombinant Mouse Adiponectin/Acrp30/AdipoQ (C-6His; Human Cells)
Product Sizes
10 µg
£499.00
32-8467-10UG
50 µg
£656.00
32-8467-50UG
About this Product
- SKU:
- 32-8467
- Extra Details:
- Source: Human Cells. MW :27.6kD. Recombinant Mouse Adiponectin is produced by our Mammalian expression system and the target gene encoding Glu18-Asn247 is expressed with a 6His tag at the C-terminus. Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity; with direct anti-diabetic; anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle; enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages; and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth; angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities; depending on the type of complex: LMW; MMW or HMW.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Cells
- Manufacturer's Data Sheet:download_pdf.php
