Recombinant Human Complement Factor H/CFH (C-6His)
Product Sizes
10 µg
£604.00
32-8457-10UG
50 µg
£897.00
32-8457-50UG
About this Product
- SKU:
- 32-8457
- Extra Details:
- Source: Human Cells. MW :50kD. Recombinant Human Complement factor H is produced by our Mammalian expression system and the target gene encoding Glu19-Leu449 is expressed with a 6His tag at the C-terminus. Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver and secreted in plasma. Its principal function is to regulate the Alternative Pathway of the complement system; ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessing both cofactor activity for the Factor I mediated C3b cleavage; and decay accelerating activity against the alternative pathway C3-convertase; C3bBb. Factor H exerts its protective action on self cells and self surfaces but not on the surfaces of bacteria or viruses; because it binds to glycosaminoglycans (GAGs) that are generally present on host cells but not; normally; on pathogen surfaces.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
