Recombinant Human Interleukin-5/IL-5 (C-6His)
Product Sizes
10 µg
£554.00
32-8439-10UG
50 µg
£847.00
32-8439-50UG
About this Product
- SKU:
- 32-8439
- Extra Details:
- Source: Human Cells. MW :14.2kD. Recombinant Human Interleukin-5 is produced by our Mammalian expression system and the target gene encoding Ile20-Ser134 is expressed with a 6His tag at the C-terminus. IL-5 is expressed in eosinophils; NK cells; TC2 CD8+ T cells; mast cells; CD45+ CD4+ T cells; gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells; IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition; it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1;the upregulation of receptors for IgA and IgG;the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
