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Recombinant Human Tripartite Motif-Containing Protein 5/TRIM5/RNF88 (N-6His)

Product Sizes
10 µg
£604.00
32-8323-10UG
50 µg
£897.00
32-8323-50UG
About this Product
SKU:
32-8323
Extra Details:
Source: E. coli. MW :30.8kD. Recombinant Human TRIM5 is produced by our E.coli expression system and the target gene encoding Met1-Gln248 is expressed with a 6His tag at the N-terminus. Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger; 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process; therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively; but capsid protein from restricted viruses is removed by proteasome-dependent degradation
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules