Recombinant Human Calreticulin-3/CALR3/CRT2
Product Sizes
10 µg
£500.00
32-8259-10UG
50 µg
£691.00
32-8259-50UG
About this Product
- SKU:
- 32-8259
- Extra Details:
- Source: E. coli. MW :42.9kD. Recombinant Human calreticulin-3 is produced by our E.coli expression system and the target gene encoding Thr20-Leu384 is expressed. Calreticulin-3 belongs to the calreticulin family; members of which are calcium binding chaperones localized mainly in the endoplasmic reticulum. It can be divided into a N-terminal globular domain; a proline-rich P-domain forming an elongated arm-like structure and a C-terminal acidic domain. During spermatogenesis process; Calreticulin-3 may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Defects in CALR3 are the cause of familial hypertrophic cardiomyopathy type 19 (CMH19); it is a hereditary heart disorder characterized by ventricular hypertrophy; which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea; syncope; collapse; palpitations; and chest pain.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
