Recombinant Human Tyrosine-Protein Kinase Blk/BLK (C-6His)
Product Sizes
10 µg
£558.00
32-8170-10UG
50 µg
£772.00
32-8170-50UG
About this Product
- SKU:
- 32-8170
- Extra Details:
- Source: E. coli. MW :58.7kD. Recombinant Human B Lymphocyte Kinase is produced by our E.coli expression system and the target gene encoding Gly2-Pro505 is expressed with a 6His tag at the C-terminus. Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain; one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase; which is involved in B-lymphocyte development; differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases; and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B transition; as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11).
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
