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Proteins and Peptides

Recombinant Human Complement Factor H-related 5/CFHR5 (C-6His)

Product Sizes
10 µg
£499.00
32-7910-10UG
50 µg
£656.00
32-7910-50UG
About this Product
SKU:
32-7910
Extra Details:
Source: Human Cells. MW :63.5kD. Recombinant Human CFHR5 is produced by our Mammalian expression system and the target gene encoding Glu19-Glu569 is expressed with a 6His tag at the C-terminus. Complement factor H-related protein 5(FHR-5 for short); is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components; suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome; atypical forms have a poorer prognosis; with higher death rates and frequent progression to end-stage renal disease.
Shipping Conditions:
Ambient
Storage Conditions:
Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins