Recombinant Human ICOS/CRP-1/AILIM/CD278 (C-Fc)
Product Sizes
10 µg
£499.00
32-7878-10UG
50 µg
£656.00
32-7878-50UG
About this Product
- SKU:
- 32-7878
- Extra Details:
- Source: Human Cells. MW :40.8kD. Recombinant Human Inducible T-cell costimulator is produced by our Mammalian expression system and the target gene encoding Glu21-Phe141 is expressed with a Fc tag at the C-terminus. Inducible T-cell costimulator; also known as activation-inducible lymphocyte immunomediatory molecule; CD278; AILIM; CVID1 and ICOS; belongs to the CD28 and CTLA4 cell surface receptor family.. ICOS contains one Ig-like V-type domain and exsits as a homodimer with disulfide-linked. ICOS is highly expressed on tonsillar T-cellsand can be induced by PMA and ionomycin; ICOS plays an important role in cell-cell signaling; immune responses; and regulation of cell proliferation. Defects in ICOS are the cause of immunodeficiency common variable type 1; which is a primary immunodeficiency characterized by antibody deficiency; hypogammaglobulinemia; recurrent bacterial infections and an inability to mount an antibody response to antige
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
