Recombinant Human Serine Hydroxymethyltransferase Cytosolic/SHMT1 (C-6His)
Product Sizes
10 µg
£554.00
32-7706-10UG
50 µg
£847.00
32-7706-50UG
About this Product
- SKU:
- 32-7706
- Extra Details:
- Source: Human Cells. MW :53.9kD. Recombinant Human SHMT1 is produced by our Mammalian expression system and the target gene encoding Met3-Phe483 is expressed with a 6His tag at the C-terminus. Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5;10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine; thymidylate; and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
