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Proteins and Peptides

Recombinant Human ER a-1;2-Mannosidase/MAN1B1 (C-6His)

Product Sizes
10 µg
£564.00
32-7699-10UG
50 µg
£787.00
32-7699-50UG
About this Product
SKU:
32-7699
Extra Details:
Source: Human Cells. MW :68.7kD. Recombinant Human MAN1B1 is produced by our Mammalian expression system and the target gene encoding Asp106-Ala699 is expressed with a 6His tag at the C-terminus. Endoplasmic Reticulum Mannosyl-Oligosaccharide 1;2-a-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning; it is also associated with impairments in adaptative behavior and manifested during the developmental period.
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins