Recombinant Human Calmodulin/CALM1
Product Sizes
10 µg
£499.00
32-7696-10UG
50 µg
£669.00
32-7696-50UG
About this Product
- SKU:
- 32-7696
- Extra Details:
- Source: E.coli. MW :16.8kD. Recombinant Human Calmodulin is produced by our E.coli expression system and the target gene encoding Met1-Lys149 is expressed. Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+; and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+; Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small; highly conserved protein that is 148 amino acids long. The protein has two approximately symmetrical globular domains each containing a pair of EF-hand motifs (the N- and C-domain) separated by a flexible linker region for a total of four Ca2+ binding sites. Calmodulin mediates many crucial processes such as inflammation; metabolism; apoptosis; smooth muscle contraction; intracellular movement; short-term and long-term memory; and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations; including the cytoplasm; within organelles; or associated with the plasma or organelle membranes; but it is always found intracellularly.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
