Recombinant Human 15-PGDH/HPGD (C-6His)
Product Sizes
10 µg
£612.00
32-7677-10UG
50 µg
£919.00
32-7677-50UG
About this Product
- SKU:
- 32-7677
- Extra Details:
- Source: Human Cells. MW :30kD. Recombinant Human HPGD is produced by our Mammalian expression system and the target gene encoding Met1-Gln266 is expressed with a 6His tag at the C-terminus. 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; also known as Prostaglandin dehydrogenase 1; 15-PGDH; HPGD and PGDH1; belongs to the short-chain dehydrogenases/reductases (SDR) family. HPGD localizes to the cytoplasm and can be found in colon epithelium; existing as a homodimer. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. HPGD is down-regulated by cortisol; dexamethasone and betamethasone; up-regulated by TGFB1. HPGD inhibits in vivo proliferation of colon cancer cells. HPGD is the key enzyme for the inactivation of prostaglandins; and thus regulates processes such as inflammation or proliferation.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
