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Recombinant Human S100 Calcium Binding Protein A8/A9 Heterodimer (C-6His)

Product Sizes
10 µg
£564.00
32-7651-10UG
50 µg
£787.00
32-7651-50UG
About this Product
SKU:
32-7651
Extra Details:
Source: E.coli. MW :11.7&13.2kD. Recombinant Human S100A8 & S100A9 Heterodimer is produced by our E.coli expression system and the target gene encoding Met1-Glu93(S100A8)&Thr2-Pro114(S100A9) is expressed with a 6His tag at the C-terminus. S100A8 is a member of the S100 family; EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes; and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism; modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules