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Proteins and Peptides

Recombinant Mouse Serine Protease Inhibitor A3N/Serpin A3N (C-6His)

Product Sizes
10 µg
£612.00
32-7572-10UG
50 µg
£919.00
32-7572-50UG
About this Product
SKU:
32-7572
Extra Details:
Source: Human Cells. MW :45.6kD. Recombinant Mouse Serine Protease Inhibitor A3N is produced by our Mammalian expression system and the target gene encoding Phe21-Lys418 is expressed with a 6His at the C-terminus. Serine protease inhibitor A3N(Serpin A3N) is a serine protease inhibitor that is structurally related to a1 antichymotrypsin encoded by the SERPINA3 gene. Serpin A3N is highly expressed in brain; testis; lung; thymus; and spleen. It is expressed with low levels in bone marrow; kidney and skeletal muscle. Serpin A3N secreted by Sertoli cells may regulate the activity of locally produced Granzyme B. Granzyme B inhibition by Serpin A3N may therefore regulate Granzyme Bmediated killing by cytotoxic lymphocytes; providing a means to disable cellmediated immune responses.
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins