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Proteins and Peptides

Recombinant Human Chymotrypsin-C/CTRC (C-6His)

Product Sizes
10 µg
£612.00
32-7470-10UG
50 µg
£919.00
32-7470-50UG
About this Product
SKU:
32-7470
Extra Details:
Source: Human Cells. MW :29kD. Recombinant Human Chymotrypsin-C is produced by our Mammalian expression system and the target gene encoding Cys17-Leu268 is expressed with a 6His tag at the C-terminus. Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity; but prefers tocleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas; and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins